Awarded in 2026
Home Department: Bioengineering
Faculty Advisors: Bo Wang (Bioengineering) and Anshul Kundaje (Genetics and Computer Science)

Research Title: Deep-Learning Guided Design of Synthetic Wound-Responsive Promoters

Wound-responsive DNA elements are gaining attention for gene therapy by sensing injury and controlling desired gene expression rapidly, but they are difficult to discover endogenously. To overcome this limitation, Jeongwoong proposes a workflow to train a sequence-to-expression model that can predict transcriptional wound response with DNA sequences and use it to guide the generation of optimized synthetic sequences as wound-responsive promoters.